exercises and solutions  (MathWorks Inc)

Journal: Journal of Parkinson's Disease

Article Title: Clinical Trial Highlights – Interventions Promoting Physical Activity in Parkinson’s Disease

doi: 10.3233/JPD-239001

Figure Lengend Snippet: Overview of clinical trials on interventions promoting physical activity

Article Snippet: 5. , STEPWISE , Radboud University Medical Center , NCT04848077 , mHealth smartphone based exercise solution , N/A , 452 , July 2026 , Yes.

Techniques: Clinical Proteomics, Activity Assay

Journal: Pulmonary Circulation

Article Title: BREEZE: Open‐label clinical study to evaluate the safety and tolerability of treprostinil inhalation powder as Tyvaso DPI™ in patients with pulmonary arterial hypertension

doi: 10.1002/pul2.12063

Figure Lengend Snippet: Baseline demographics and disease characteristics

Article Snippet: Treprostinil has been shown to be both safe and effective when administered parenterally, , but an oral inhalation solution was developed to deliver the drug directly to the site of action, avoiding the most common adverse events (AEs) of infusion‐site pain and reaction seen with subcutaneous treprostinil administration., Treprostinil inhalation solution was approved in 2009 for the treatment of PAH to improve exercise ability based on the results of the TRIUMPH study, which demonstrated a placebo‐corrected median change from baseline in 6‐minute walk distance (6MWD) of 20 m ( p < 0.001) after 12 weeks of treatment., Treprostinil inhalation solution is delivered via a handheld ultrasonic nebulizer (Tyvaso® Inhalation System, United Therapeutics Corporation).

Techniques: Functional Assay